The Commissioners are appointed by the Governing Body of the CCMA on the strength of their experience and expertise in labour matters, particularly dispute prevention and dispute resolution. The commissioners are obliged to carry out their job with complete impartiality and they are bound to "the Commissioner Code of Conduct".

Each provincial office has a team of full time commissioners supported by an additional complement of part-time commissioners. They conciliate, facilitate, mediate and in some instances arbitrate, to prevent and settle industrial disputes. Convening Senior Commissioners (CSCs) have been appointed in each province and their role is to monitor the professional standards of the CCMA and to assist in the allocation of cases to commissioners.